tag:blogger.com,1999:blog-1196883866505951580.post8262731856817498075..comments2023-09-30T04:58:28.058-05:00Comments on My Reputo: Generic Peanut Butter is Not the Same as Generic DrugsReputohttp://www.blogger.com/profile/06845157593799270355noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-1196883866505951580.post-82082566183330356112010-10-14T10:18:44.225-05:002010-10-14T10:18:44.225-05:00Except that the bioavailability or bioequivalence ...Except that the bioavailability or bioequivalence standard (the variation you are talking about which I believe is actually up to 20%) applies to the name brand manufacturers as well. Example: Name Brand Company creates a drug with active ingredient A at a dose of 10 mg. They are allowed to manufacture it with a dose of 8 mg to 12 mg and still call it 10 mg (so long as their studies have shown that the 8 mg and 12 mg have no statistical difference in the effects). Once it goes generic, the generic companies can do the same thing. The Name Brand is not held to a higher standard, they just spend all of the research dollars to show that 8mg and 12mg are pharmacologically identical to 10mg. Otherwise cost of manufacture would be prohibitable expensive to ensure that you ALWAYS have exactly 10 mg.Reputohttps://www.blogger.com/profile/06845157593799270355noreply@blogger.comtag:blogger.com,1999:blog-1196883866505951580.post-21194987633128378322010-10-13T12:34:36.249-05:002010-10-13T12:34:36.249-05:00One of the things you don't mention is the all...One of the things you don't mention is the allowable variance of strength allowed for generics. Generics are allowed a 10% variation from the stated dosage of the name brand. This can cause significantly different results in the patient due to the higher or lower dosage then the name brand. Adding to that is the patient might not get the same generic brand each time they fill a prescription causing more problems.ParatrooperJJnoreply@blogger.com